Develop new applications with Xdrop®

Droplet technology made easy

An open system to easily generate droplets your way

The Xdrop system is a highly versatile, open platform that generates droplets for high-throughput processing and screening of molecules, enzymes, cells and more. In a simple workflow, the instrument operates with dedicated cartridges to:

  • produce droplets in your choice of buffers, media, reagents or other
  • enable flexible production throughput – use 1 cartridge lane or use all 8 lanes
  • generate millions of double-emulsion droplets that are sturdy enough to be sorted on a FACS
  • yield up to 100 thousand single-emulsion droplets in just 45 seconds

How can I try out ideas for Xdrop droplets?

Take a look below at how Samplix currently uses droplets and think about novel ways in which your research could benefit from this fast, open-platform droplet generator. For example, you can:

  • Isolate reactions to improve outcomes
  • Culture one or more cells in a controlled environment
  • Create massively parallelized, high-throughput workflows
  • Work with single molecules
  • Sort molecules, cells, or particles

Then contact us and tell us about your idea! Samplix will work with you to access an Xdrop instrument.

What Samplix currently does with droplets

Video thumbnail

What do Xdrop droplets look like?

Droplet schematic(1)

 

DOUBLE-EMULSION DROPLETS

SINGLE-EMULSION DROPLETS

Compatible with DNA, RNA, proteins

   

Compatible with cells up to 6 µm in diameter and nuclei

Compatible with cells >6 µm and <75 µm in diameter

Variability in size below 5%

Variability in droplet number per run under 25%
Compatible with common growth media
Compatible with detergents
Permeability to gases and some fluorophores N/A
Compatibility with FACS sorting

 

Get more details in our fact sheet

High-throughput screening of molecules, cells and particles is one of the most promising applications for droplets that demands rapid production of large numbers of droplets. Xdrop meets that requirement. Learn more by downloading our High-Throughput Screening Manual.

What do researchers do with droplets?

Nanoparticle

Precision nanoparticles are assembled under controlled conditions in droplet microreactors

Evolution

Enzymes are evolved in droplet microenvironments to be screened at high throughput and speed

Incubation

Prokaryotic and eukaryotic cells are cultured and characterized in droplet microincubators

Antibody

Cell-free synthesis of proteins and lipid particles is done in droplet microfactories