Xdrop enables function-first analysis at single-cell resolution, providing key insights into population heterogeneity. It reveals how individual cells interact and regulate the production of granzyme B, cytokines, antibodies, and signaling molecules. These insights are critical for advancing next-generation therapeutics — from novel antibodies to cutting-edge immunotherapies.
The Xdrop is a droplet microfluidics instruments capable of compartmentalizing single cells in droplets. Cells can be cultured and assayed within the droplets, retaining any secreted proteins or molecules. Uniquely, our platform enables the analysis and sorting of these droplets on flow cytometer and sorters, making it ideal for cell function assays.
Xdrop technology specializes in double emulsion droplet generation. These droplets are dispersed in an aqueous phase, ensuring compatibility with flow cytometers. This significantly broadens the range of assays achievable, enabling the analysis of secreted antibodies, cytokines, and other proteins, all confined within the droplets. It also facilitates the analysis of cell-cell interactions and cell killing assays, empowering the field of immunotherapy
The Xdrop platform combined with new capability of the MA900 Cell Sorter enables an integrated workflow for isolation of double-emulsion droplets with high efficiency and exceptional recovery rates. They can be used together to support high-throughput studies in immunotherapy, antibody discovery, and cellular research. Discover more in this application brochure.
For all inquiries regarding the workflow, please contact Samplix.
Contact our dedicated support team, which includes field application scientists, cell biologists, and microfludics experts, to discuss your workflow needs. They can help you plan your experiments, from deciding on the best media and fluorophores to discussing downstream analyses.
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