Whether you're screening mammalian or microbial cells Xdrop microfluidics products can boost your speed and accuracy.
Improve the throughput and efficiency of mammalian and microbial cell screening. Encapsulate millions of living cells in microfluidics droplets that are compatible with flow cytometers and cell sorters, meaning you can screen and retrieve the cells with the desired properties for further analysis.
Improving the throughput and efficiency of screening for rare, active enzyme variants in very large libraries.
During bulk cultivation, bacterial cells producing inactive enzyme variants can outgrow cells producing active but rare variants, making screening ineffective.
Xdrop greatly increases the throughput for fluorescence-based screening, improving enzyme engineering efficiency.
With single-cell assays in droplets, Xdrop reveals the heterogeneity of CAR T cells. In this study we showed that only about 20% kill their targets within 6 hours, while 33% secrete active granzyme B. Such detailed insights into cellular heterogeneity are not achievable with traditional bulk assays.
View our published papers.
Explore immune cell function in single-cell format assays, including cytokine, granzyme B, and cell killing assays.
Accelerate discovery with high-throughput screening. Encapsulate millions of antibody-secreting cells to uncover rare, high-value variants.
Advance genomics workflows with precise single DNA fragment encapsulation. Ideal for insert validation and targeted enrichments.
