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Samplix ApS empowers the life sciences and medical research communities with cutting-edge microfluidics-based solutions. At Samplix, our mission is to elevate the resolution and throughput of genomics, cell screening, and molecular engineering workflows, providing researchers with unparalleled insights into the intricate world of cells and genomes.
Our proprietary Samplix technology is meticulously crafted to offer targeted DNA and single-cell insights. Through the generation of highly stable microfluidic double-emulsion droplets, we encapsulate biological material with precision, including single-cells, organelles, and single molecules. These microfluidic wonders pave the way for a myriad of high-resolution downstream analyses, ranging from assessments of single-cell functional heterogeneity to the acceleration of enzyme engineering.
At Samplix, we are more than just developers of microfluidics solutions; we are dedicated partners ready to assist academic, corporate, and government researchers in achieving their goals. Our expertise extends across diverse fields such as human genomics, gene and cell therapy, plant genomics, and synthetic biology.
How do you get error- and bias-free identification of genomic variants? This was the question that Dr. Marie Just Mikkelsen and Dr. Thomas Kvist wanted to answer in 2012, when they were working on rare genomic variants. At the time, no existing technology could address that important question. Motivated by the challenge, the two scientists set out to develop a method that reveals any genomic variation.
PCR and unintended interactions between DNA molecules during sample handling are often the root of bias and errors in genomic analyses. Marie and Thomas built a team focused on creating a PCR amplification-free workflow with single molecules encapsulated in droplets.
In 2019, after 6 years of product development and thorough testing, the fully developed microfluidics system for droplet-based, PCR-free enrichment of genomic regions was launched under the name Xdrop®.
Since then, Xdrop technology has proven itself in a broad range of applications with human, other animal, plant, and microbial genomes. It also supports the investigation of cell reactions, including enzyme activity and protein synthesis.
With the success of the microfluidics system, Samplix has grown considerably, supporting customers worldwide with their genomics and molecular biology research.
Lars Kongsbak provides expertise in building startups, including strategy drafting and establish competent leadership. He has listed two life science companies and is or has been engaged with BlueBee, ViroGates, Exiqon, Novozymes and Novo Nordisk.
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CTO and co-founder
Marie Just Mikkelsen provides expertise in product development, which for Samplix includes instruments, microfluidics technology, molecular biology reagents, and bioinformatics. She has been engaged with Biogasol and Estibio.
Trine Overgaard Østerbye provides expertise in leading commercial operations in life sciences startup companies, including companies working within the areas of immunology other cell functionality space. She has been engaged with BioPorto Diagnostics, Svar Life Sciences, and Kementec Solutions.
VP Intellectual Property Rights
Søren Echwald Morgenthaler provides expertise in patent strategy, freedom to operate analysis and business strategy. He has listed one life sciences company and is or has been engaged with Anapa Biotech, Exiqon and Novo Nordisk.
VP Application & Market Development
Peter Mouritzen provides expertise in documenting the many applications of the Xdrop technology and builds relationships with key opinion leaders across the globe. He has listed one life science company and has been engaged with QIAGEN and Exiqon.
Chairman & Co-Founder
Michael Obermayer is an experienced board member with extensive knowledge in Business Strategy, and Corporate Development. With previous roles at McKinsey & Co., and Fjord Capital Partners, Michael brings a wealth of global experience and strategic acumen to Samplix ApS.
Lars Krogsgaard is a professional board member with extensive experience in strategic development, business development, risk management, and financing. With a proven track record as an active investor and board member in over 25 Nordic companies, Lars brings valuable insights to Samplix ApS.
With 25 years of experience in the life science research and biotechnology tools industry, Rodney brings invaluable expertise to Samplix ApS. His decade-long tenure in biotech start-ups, consulting, and corporate settings, focusing on life science business development, sales, marketing, and strategy development, enriches the board with diverse perspectives and insights.
See the latest news about product releases, webinars and events, partnerships and more.
February 22, 2024 - Join the upcoming webinar with Dr. Anzaan Dippenar, Senior Research at University of Antwerp and learn more about revolutionizing tuberculosis (TB) surveillance with Whole Genome Sequencing
Title: Droplet-based Whole Genome Amplification: Successfully Sequencing Minute Amounts of Mycobacterium Tuberculosis DNA
Speaker: Dr. Anzaan Dippenaar, Senior Researcher, University of Antwerp
When: Wednesday, March 20, 2024. 10:30am EDT / 2:30pm GMT, 3:30pm CET
February 14, 2024 - Discover the last Drug Target Review’s eBook entitled “Reveal Cell Function With Single-Cell Resolution” and explore the synergy of microfluidics technology and single-cell format flow cytometry for unprecedented insights into immune cell populations’ heterogeneity.
See how our Xdrop DE50 droplets can be used to encapsulate individual immune cells and deliver them for incubation, analysis, and retrieval.Download here
January 25, 2024 - Join the upcoming webinar with our colleague Volkan Besirlioglu and learn more about how to use Xdrop for enzyme screening.
Title: Enzyme Engineering Advancements with Xdrop and Flow CytometrySpeaker: Volkan Besirlioglu, Field Application Scientist, Samplix When: Wednesday, February 21, 2024. 9:30am EST (NA) / 2:30pm GMT (UK) / 3:30pm CET (EU-central)
January 5, 2024 – In 2023, the EIC (European Innovation Council) committed to aiding Samplix in the development of our microfluidics technology for functional characterization of single cells. This technology is crucial for revealing the heterogeneity of immune cells fighting cancer, among other key applications. The incredible potential of cell and immune therapy is currently limited by technical challenges related to the standard analysis of immune cells in bulk, which neglects their heterogeneity.
Having made good progress in the EIC Accelerator-funded project in 2023, Samplix is opening 2024 with a tight focus on the ways our Xdrop instruments can best serve the cell therapy research community. We’re proud to have been chosen by the EIC and committed to ensuring vastly improved workflows for cell therapy research, including cytokine, granzyme, antibody, and cell killing applications.
December 5, 2023 – In this webinar, Dr. Garret Guenther (Agilent) demonstrates how the power of Agilent’s NovoCyte Quanteon flow cytometry coupled with Samplix’s Xdrop double-emulsion droplets helps characterize cytokine secretion and cell–cell interaction. Dr. Bárbara Schlicht (Samplix) presents our latest data on single-cell functional screening assays.
Watch the webinar
October 25, 2023 – Don't miss our next webinar on November 8, at 16:00 GMT / 17:00 CET / 11:00 EST
In this webinar, Dr. Bárbara Schlicht, Samplix and Dr. Garret Guenther, Agilent Technologies, will discuss how the two technologies, Xdrop combined with NovoCyte, enable cytokine secretion assays as well as cell-cell interaction assays. Furthermore, they will explore how this innovation has the potential to transform single-cell droplet microfluidics by expanding the scope of single-cell functional screening assays and unlocking new frontiers in the understanding of single-cell behavior and function.
September 12, 2023 – Dr. David Leander Petersen, a member of our Applications Development team, is speaking at the virtual Cell Therapy Analytics Symposium next week. David's talk, Characterizing the functional heterogeneity of cell populations with Xdrop, focuses on showing how our microfluidics technology can support cell therapy research. He will show how our double-emulsion (DE) droplets are compatible with single-cell format assays for characterizing cell function, with results from cytokine secretion, cell-killing, and granzyme B secretion assays.
Oxford Global's virtual Cell Therapy Analytics Symposium is on Tuesday, September 19, running from 11 a.m. to 5 p.m. UK time.
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