Encapsulate single-cells in double-emulsion droplets compatible with standard flow cytometry, sorters and imaging platforms.
The Xdrop instrument is a microfluidic platform generating double emulsion droplets for the encapsulation cells and DNA.
The Xdrop instrument is a user-friendly microfluidic droplet generator for high-throughput single-cell functional analysis. It rapidly encapsulates individual cells, organelles or DNA into uniform double-emulsion (water-in-oil-in-water) picoliter droplets.
These droplets are fully compatible with standard flow cytometers and cell sorters, allowing direct phenotypic screening of secretions, cell–cell interactions, cytotoxicity and more. After sorting, cells remain viable (∼90%) for downstream assays like scRNA-seq or clonal expansion. Xdrop thus enables researchers to discover rare, functionally defined cells – from novel antibodies to immune cells – in a single-cell format.
