Accessible to every lab, Xdrop enables screening of millions of antibody-secreting cells and isolation of high-value variants.
Identify and isolate rare antibody-secreting cells from your primary sample. Encapsulate millions of single cells in double emulsion droplets for high-throughput screening with flow cytometry or cell sorting. Effortlessly recover living cells producing the desired antibodies for downstream analysis and expansion.
Discover how Xdrop® enables high-throughput discovery of antibodies against membrane protein targets through functional screening of antibody-secreting cells. This application note demonstrates both bead-based and native cell-based antigen presentation approaches, enabling the identification of HER2-targeting antibodies in a one-day workflow.
Accelerate antibody discovery with a one-day workflow for screening millions of antibody-secreting cells. See how Xdrop® combines functional screening with single-cell V(D)J sequencing to uncover diverse, high-affinity antibodies targeting distinct epitopes.
Figure: Image of droplets containing the Xdrop ASC screening assay taken with Xcyto5, ChemoMetec. Cells secreting anti-hTNFα-antibodies clearly show an accumulated fluorescent signal on the TNFα-coated microspheres.
Transform discovery workflows. Effortlessly encapsulate single-cell libraries, enhancing the speed of your screening campaigns.
Explore immune cell function in single-cell format assays, including cytokine, granzyme B, and cell killing assays.
Advance genomics workflows with precise single DNA fragment encapsulation. Ideal for insert validation and targeted enrichments.
